The effects of Caffeoylserotonin on inhibition of melanogenesis through the downregulation of MITF via the reduction of intracellular cAMP and acceleration of ERK activation in B16 murine melanoma cells
In this study, we evaluated the anti-melanogenesis effects ofCaffeoylserotonin (CaS) in B16 melanoma cells. Treatment withCaS reduced the melanin content and tyrosinase (TYR) activity inB16 melanoma cells in a dose-dependent manner. CaS inhibitedthe expression of melanogenesis-related proteins, incl...
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| Format: | Article |
| Language: | English |
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Korean Society for Biochemistry and Molecular Biology
2012-12-01
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| Series: | BMB Reports |
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| Online Access: | http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTE0MTVAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0xMiU1RDEyMTIyNjE2MzNfJTI4NzI0LTcyOSUyOUJNQl8xMi0wMzkucGRm |