CD4+ T Responses Other Than Th1 Type Are Preferentially Induced by Latency-Associated Antigens in the State of Latent Mycobacterium tuberculosis Infection

CD4+ T Responses Other Than Th1 Type Are Preferentially Induced by Latency-Associated Antigens in the State of Latent Mycobacterium tuberculosis Infection

Mycobacterium tuberculosis (M. tuberculosis) produces a diverse range of antigenic proteins in its dormant phase. The cytokine profiles of CD4+ T cell responses, especially subsets other than Th1 type (non-Th1 type), against these latency-associated M. tuberculosis antigens such as α-crystallin (Acr...

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Bibliographic Details
Main Authors: Yoshiro Yamashita, Toshiyuki Oe, Kenji Kawakami, Mayuko Osada-Oka, Yuriko Ozeki, Kazutaka Terahara, Ikkoh Yasuda, Tansy Edwards, Takeshi Tanaka, Yasuko Tsunetsugu-Yokota, Sohkichi Matsumoto, Koya Ariyoshi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
latent M. tuberculosis infection
CD4+ T cells
non-Th1
Acr
HBHA
MDP-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02807/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02807/full

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