Influence of polymorphisms in innate immunity genes on susceptibility to invasive aspergillosis after stem cell transplantation.

The innate immune system plays a pivotal role in the primary defence against invasive fungal infection. Genetic variation in genes that regulate this response, initiated by pulmonary macrophages, may influence susceptibility to invasive aspergillosis in patients at risk. We investigated in a clinica...

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Bibliographic Details
Main Authors: Mark G J de Boer, Hetty Jolink, Constantijn J M Halkes, Pim L J van der Heiden, Dennis Kremer, J H Frederik Falkenburg, Esther van de Vosse, Jaap T van Dissel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3070725?pdf=render