A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi

Plasmodium liver hypnozoites, which cause disease relapse, are widely considered to be the last barrier towards malaria eradication. The biology of this quiescent form of the parasite is poorly understood which hinders drug discovery. We report a comparative transcriptomic dataset of replicating liv...

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Bibliographic Details
Main Authors: Annemarie Voorberg-van der Wel, Guglielmo Roma, Devendra Kumar Gupta, Sven Schuierer, Florian Nigsch, Walter Carbone, Anne-Marie Zeeman, Boon Heng Lee, Sam O Hofman, Bart W Faber, Judith Knehr, Erica Pasini, Bernd Kinzel, Pablo Bifani, Ghislain M C Bonamy, Tewis Bouwmeester, Clemens H M Kocken, Thierry Tidiane Diagana
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
malaria
liver stages
hypnozoites
transcriptomics
plasmodium
Plasmodium cynomolgi
Online Access:https://elifesciences.org/articles/29605

Internet

https://elifesciences.org/articles/29605

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