Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

The molecular identity of renal glomerular cells is poorly characterized and rodent glomerulopathy models translate poorly to humans. Here, the authors show molecular signatures of glomerulus-associated cells using single cell RNA sequencing and highlight differences between mouse and human cells.

Bibliographic Details
Main Authors: Bing He, Ping Chen, Sonia Zambrano, Dina Dabaghie, Yizhou Hu, Katja Möller-Hackbarth, David Unnersjö-Jess, Gül Gizem Korkut, Emmanuelle Charrin, Marie Jeansson, Maria Bintanel-Morcillo, Anna Witasp, Lars Wennberg, Annika Wernerson, Bernhard Schermer, Thomas Benzing, Patrik Ernfors, Christer Betsholtz, Mark Lal, Rickard Sandberg, Jaakko Patrakka
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22331-9

Internet

https://doi.org/10.1038/s41467-021-22331-9

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