Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in Mice with Experimental Colitis

Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in Mice with Experimental Colitis

Dendritic cells (DCs) play a pivotal role as initiators in the pathogenesis of inflammatory bowel disease and are regulated by the JAK/STAT/SOCS signaling pathway. As a potent anti-inflammatory compound, curcumin represents a viable treatment alternative or adjunctive therapy in the management of ch...

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Bibliographic Details
Main Authors: Hai-mei Zhao, Rong Xu, Xiao-ying Huang, Shao-min Cheng, Min-fang Huang, Hai-yang Yue, Xin Wang, Yong Zou, Ai-ping Lu, Duanyong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Pharmacology
Subjects:
Curcumin
dendritic cell
costimulatory molecules
experimental colitis
JAK/STAT/SOCS signal
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00455/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00455/full

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