Autophagy occurs in lymphocytes infiltrating Sjögren’s syndrome minor salivary glands and correlates with histological severity of salivary gland lesions

Autophagy occurs in lymphocytes infiltrating Sjögren’s syndrome minor salivary glands and correlates with histological severity of salivary gland lesions

Abstract Backgrounds The organization of minor salivary glands (MSG) infiltrates, in patients with Sjögren’s syndrome (SS), associates with disease severity and progression. Aberrant regulation of lymphocyte autophagy is involved in autoimmunity, and in previous work, we provided the first evidence...

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Bibliographic Details
Main Authors: Serena Colafrancesco, Marta Vomero, Valentina Iannizzotto, Antonina Minniti, Cristiana Barbati, Francesca Arienzo, Linda Mastromanno, Tania Colasanti, Raffaella Izzo, Saba Nayar, Elena Pipi, Bruna Cerbelli, Carla Giordano, Francesco Ciccia, Fabrizio Conti, Guido Valesini, Francesca Barone, Roberta Priori, Cristiano Alessandri
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Arthritis Research & Therapy
Subjects:
Autophagy
Lymphocytes
Sjögren’s syndrome
Minor salivary gland
LC3B
Atg5
Online Access:http://link.springer.com/article/10.1186/s13075-020-02317-6

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http://link.springer.com/article/10.1186/s13075-020-02317-6

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