Integrin-Targeting Dye-Doped PEG-Shell/Silica-Core Nanoparticles Mimicking the Proapoptotic Smac/DIABLO Protein

Integrin-Targeting Dye-Doped PEG-Shell/Silica-Core Nanoparticles Mimicking the Proapoptotic Smac/DIABLO Protein

Cancer cells demonstrate elevated expression levels of the inhibitor of apoptosis proteins (IAPs), contributing to tumor cell survival, disease progression, chemo-resistance, and poor prognosis. Smac/DIABLO is a mitochondrial protein that promotes apoptosis by neutralizing members of the IAP family....

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Bibliographic Details
Main Authors: Rossella De Marco, Enrico Rampazzo, Junwei Zhao, Luca Prodi, Mayra Paolillo, Pierre Picchetti, Francesca Gallo, Natalia Calonghi, Luca Gentilucci
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nanomaterials
Subjects:
Smac/DIABLO
cancer
RGD
AVPI
IAP
confocal microscopy
Online Access:https://www.mdpi.com/2079-4991/10/6/1211

Internet

https://www.mdpi.com/2079-4991/10/6/1211

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