Transcriptomic Analysis of Ovine Hepatic Lymph Node Following Fasciola hepatica Infection – Inhibition of NK Cell and IgE-Mediated Signaling

Transcriptomic Analysis of Ovine Hepatic Lymph Node Following Fasciola hepatica Infection – Inhibition of NK Cell and IgE-Mediated Signaling

Fasciola hepatica is a trematode parasite responsible for major economic losses in livestock production, and is also a food-borne zoonotic agent in developing rural regions. For years, the immunoregulatory mechanisms employed by the parasite have hampered efforts to develop a successful vaccine cand...

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Bibliographic Details
Main Authors: Amalia Naranjo-Lucena, Carolina N. Correia, Verónica Molina-Hernández, Álvaro Martínez-Moreno, John A. Browne, José Pérez, David E. MacHugh, Grace Mulcahy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
transcriptomics
sheep
lymph node
NK cells
Fasciola
IgE signalling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.687579/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.687579/full

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