Effect of High-mobility Group Box-1 on Expression of Stem Cell Markers OCT4, Sox2 and Nanog in Cervical Carcinoma

Objective To investigate the role of High-mobility group box-1 (HMGB1) protein in regulating the expression of cancer stem cell markers Nanog, OCT4 and Sox2. Methods We transferred recombinant plasmid and target-specific siRNA of HMGB1 into cervical cancer cells. The expression of cancer stem cell m...

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Bibliographic Details
Main Authors: WANG Hua, CAI Hongbing, LI Shuwei, LI Wei, GAO Qian
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2018-10-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.1374.htm