Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection

Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection

Abstract Background A pregnant gilt infected with porcine reproductive and respiratory syndrome virus (PRRSV) can transmit the virus to her fetuses across the maternal-fetal-interface resulting in varying disease outcomes. However, the mechanisms leading to variation in fetal outcome in response to...

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Bibliographic Details
Main Authors: Angelica Van Goor, Alex Pasternak, Kristen Walker, Linjun Hong, Carolina Malgarin, Daniel J. MacPhee, John C. S. Harding, Joan K. Lunney
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Genomics
Subjects:
Porcine reproductive and respiratory syndrome
Gene expression
Fetal pig
Immunity
Placenta
Thymus
Online Access:http://link.springer.com/article/10.1186/s12864-020-07154-0

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http://link.springer.com/article/10.1186/s12864-020-07154-0

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