A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint

A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint

BackgroundCD161, encoded by killer cell lectin-like receptor B1 gene, is a newly reported candidate inhibitor of tumour-infiltrating T cells. Antibody-mediated CD161 blockade enhances T cell-mediated killing of cancer cells in vitro and in vivo in several tumour types. We evaluated the role of CD161...

Full description

Bibliographic Details
Main Authors: Xiaohan Zhou, Jun Du, Chengdong Liu, Hanyi Zeng, Yuting Chen, Li Liu, Dehua Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
TCGA
immune microenvironment
CD161
immune checkpoints
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.688215/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.688215/full

Similar Items