Association between the SERPING1 gene and age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese.

PURPOSE: Recently, a complement component 1 inhibitor (SERPING1) gene polymorphism was identified as a novel risk factor for age-related macular degeneration (AMD) in Caucasians. We aimed to investigate whether variations in SERPING1 are associated with typical AMD or with polypoidal choroidal vascu...

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Main Authors: Isao Nakata, Kenji Yamashiro, Ryo Yamada, Norimoto Gotoh, Hideo Nakanishi, Hisako Hayashi, Akitaka Tsujikawa, Atsushi Otani, Masaaki Saito, Tomohiro Iida, Akio Oishi, Keitaro Matsuo, Kazuo Tajima, Fumihiko Matsuda, Nagahisa Yoshimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3079757?pdf=render