Examining the role of macrolides and host immunity in combatting filarial parasites

Abstract Macrocyclic lactones (MLs), specifically the avermectins and milbemycins, are known for their effectiveness against a broad spectrum of disease-causing nematodes and arthropods in humans and animals. In most nematodes, drugs in this class induce paralysis, resulting in starvation, impaired...

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Bibliographic Details
Main Author: Doug S. Carithers
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Parasites & Vectors
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13071-017-2116-6