Training the Fetal Immune System Through Maternal Inflammation—A Layered Hygiene Hypothesis

Over the last century, the alarming surge in allergy and autoimmune disease has led to the hypothesis that decreasing exposure to microbes, which has accompanied industrialization and modern life in the Western world, has fundamentally altered the immune response. In its current iteration, the “hygi...

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Bibliographic Details
Main Authors: April C. Apostol, Kirk D. C. Jensen, Anna E. Beaudin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00123/full