The consensus 5' splice site motif inhibits mRNA nuclear export.

In eukaryotes, mRNAs are synthesized in the nucleus and then exported to the cytoplasm where they are translated into proteins. We have mapped an element, which when present in the 3'terminal exon or in an unspliced mRNA, inhibits mRNA nuclear export. This element has the same sequence as the c...

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Bibliographic Details
Main Authors: Eliza S Lee, Abdalla Akef, Kohila Mahadevan, Alexander F Palazzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4380460?pdf=render