Circular RNA TRAPPC6B inhibits intracellular Mycobacterium tuberculosis growth while inducing autophagy in macrophages by targeting microRNA‐874‐3p

Circular RNA TRAPPC6B inhibits intracellular Mycobacterium tuberculosis growth while inducing autophagy in macrophages by targeting microRNA‐874‐3p

Abstract Objectives Genetic and epigenetic mechanisms regulate antimicrobial immunity against Mycobacterium tuberculosis (Mtb) infection. Methods The present study assessed circular RNA TRAPPC6B (circTRAPPC6B) for antimicrobial immune functions and defined mechanisms wherein circTRAPPC6B regulates M...

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Bibliographic Details
Main Authors: Hou‐Long Luo, Jiang Pi, Jun‐Ai Zhang, En‐Zhuo Yang, Huan Xu, Hong Luo, Ling Shen, Ying Peng, Gan‐Bin Liu, Cai‐Mei Song, Ke‐Yue Li, Xian‐Jin Wu, Bi‐Ying Zheng, Hong‐Bo Shen, Zheng W Chen, Jun‐Fa Xu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
autophagy
circTRAPPC6B
macrophage
miR‐874‐3p
Mycobacterium tuberculosis
Online Access:https://doi.org/10.1002/cti2.1254

Internet

https://doi.org/10.1002/cti2.1254

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