Peptide Inhibitor of Complement C1, RLS-0071, Reduces Zosteriform Spread of Herpes Simplex Virus Type 1 Skin Infection and Promotes Survival in Infected Mice

Peptide Inhibitor of Complement C1, RLS-0071, Reduces Zosteriform Spread of Herpes Simplex Virus Type 1 Skin Infection and Promotes Survival in Infected Mice

Herpes simplex virus type 1 (HSV-1) is a prevalent human pathogen primarily transmitted through skin-to-skin contact, especially on and around mucosal surfaces where there is contact with contaminated saliva during periods of viral shedding. It is estimated that 90% of adults worldwide have HSV-1 an...

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Bibliographic Details
Main Authors: Maimoona S. Bhutta, Daniel G. Sausen, Kirstin M. Reed, Elisa S. Gallo, Pamela S. Hair, Brittany P. Lassiter, Neel K. Krishna, Kenji M. Cunnion, Ronen Borenstein
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
RLS-0071
PIC1
antiviral
herpes simplex type 1
acyclovir-resistance
zosteriform infection
Online Access:https://www.mdpi.com/1999-4915/13/8/1422

Internet

https://www.mdpi.com/1999-4915/13/8/1422

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