High plasma levels of islet amyloid polypeptide in young with new-onset of type 1 diabetes mellitus.

<h4>Aims/hypothesis</h4>Islet amyloid polypeptide (IAPP) is a beta cell hormone secreted together with insulin upon glucose stimulation. IAPP participates in normal glucose regulation, but IAPP is also known for its ability to misfold and form islet amyloid. Amyloid fibrils form through...

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Main Authors: Johan F Paulsson, Johnny Ludvigsson, Annelie Carlsson, Rosaura Casas, Gun Forsander, Sten A Ivarsson, Ingrid Kockum, Åke Lernmark, Claude Marcus, Bengt Lindblad, Gunilla T Westermark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24671002/pdf/?tool=EBI