Phylogenetic analysis and predicted functional effect of protein mutations of E6 and E7 HPV16 strains isolated in Indonesia

Background: E6 and E7 are oncoproteins of HPV16. Natural amino acid variation in HPV16 E6 can alter its carcinogenic potential. The aim of this study was to analyze phylogenetically E6 and E7 genes and proteins of HPV16 from Indonesia and predict the effects of single amino acid substitution on pro...

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Bibliographic Details
Main Authors: Dwi Wulandari, Lisnawati Rachmadi, Tjahjani M. Sudiro
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2015-12-01
Series:Medical Journal of Indonesia
Subjects:
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/1197