Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells

Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells

The identification and characterisation of dormant cells is currently difficult. Here the authors report Optical Stem Cell Activity Reporter (OSCAR) to assess RNA polymerase II activity and identify dormant cell populations in intestinal epithelial cells in vivo.

Bibliographic Details
Main Authors: Rasmus Freter, Paola Falletta, Omid Omrani, Mahdi Rasa, Katharine Herbert, Francesco Annunziata, Alberto Minetti, Anna Krepelova, Lisa Adam, Sandra Käppel, Tina Rüdiger, Zhao-Qi Wang, Colin R. Goding, Francesco Neri
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23580-4

Internet

https://doi.org/10.1038/s41467-021-23580-4

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