Catalpol Inhibits Macrophage Polarization and Prevents Postmenopausal Atherosclerosis Through Regulating Estrogen Receptor Alpha

Catalpol Inhibits Macrophage Polarization and Prevents Postmenopausal Atherosclerosis Through Regulating Estrogen Receptor Alpha

Lacking estrogen increases the risk of atherosclerosis (AS) in postmenopausal women. Inflammation plays a vital role in the pathological process of AS, and macrophages are closely related to inflammation. Catalpol is an iridoid glucoside extracted from the fresh roots of the traditional Chinese herb...

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Bibliographic Details
Main Authors: Qi Chen, Xu Qi, Weiwei Zhang, Yuhan Zhang, Yunhui Bi, Qinghai Meng, Huimin Bian, Yu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
catalpol
postmenopausal atherosclerosis
macrophage polarization
estrogen receptor
inflammation
oxidatie stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.655081/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.655081/full

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