Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin

Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin

The effects of feeding cholesterol, sitosterol, and lovastatin on cholesterol absorption, biosynthesis, esterification, and LDL receptor function were examined in the rat jejunal mucosa. Cholesterol absorption was measured by the dual-isotope plasma ratio method; the rate-limiting enzyme of choleste...

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Bibliographic Details
Main Authors: Lien B. Nguyen, Sarah Shefer, Gerald Salen, G.S. Tint, Frank Ruiz, John Bullock
Format: Article
Language:English
Published: Elsevier 2001-02-01
Series:Journal of Lipid Research
Subjects:
cholesterol absorption
intestinal cholesterol biosynthesis
LDL receptor
cholesterol uptake
LDL binding
HMG-CoA reductase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520316795

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http://www.sciencedirect.com/science/article/pii/S0022227520316795

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