Epigenetic Reprogramming During Somatic Cell Nuclear Transfer: Recent Progress and Future Directions

Epigenetic Reprogramming During Somatic Cell Nuclear Transfer: Recent Progress and Future Directions

Somatic cell nuclear transfer (SCNT) has broad applications but is limited by low cloning efficiency. In this review, we mainly focus on SCNT-mediated epigenetic reprogramming in livestock and also describe mice data for reference. This review presents the factors contributing to low cloning efficie...

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Bibliographic Details
Main Authors: Xiangyu Wang, Jiadan Qu, Jie Li, Hongbin He, Zhonghua Liu, Yanjun Huan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Genetics
Subjects:
somatic cell nuclear transfer
cloning efficiency
nuclear reprogramming
epigenetic modification
long non-coding RNA
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00205/full

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https://www.frontiersin.org/article/10.3389/fgene.2020.00205/full

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