Effects of stress on behavior and resting-state fMRI in rats and evaluation of Telmisartan therapy in a stress-induced depression model

Abstract Background The etiology of depression and its effective therapeutic treatment have not been clearly identified. Using behavioral phenotyping and resting-state functional magnetic resonance imaging (r-fMRI), we investigated the behavioral impact and cerebral alterations of chronic unpredicta...

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Bibliographic Details
Main Authors: Junling Li, Ran Yang, Kai Xia, Tian Wang, Binbin Nie, Kuo Gao, Jianxin Chen, Huihui Zhao, Yubo Li, Wei Wang
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Psychiatry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12888-018-1880-y