ATM mutations improve radio-sensitivity in wild-type isocitrate dehydrogenase-associated high-grade glioma: retrospective analysis using next-generation sequencing data

ATM mutations improve radio-sensitivity in wild-type isocitrate dehydrogenase-associated high-grade glioma: retrospective analysis using next-generation sequencing data

Abstract Background To identify the association between somatic ataxia-telangiectasia mutated (ATM) mutations and improved radio-sensitivity, we retrospectively reviewed next-generation sequencing data from patients diagnosed with isocitrate dehydrogenase (IDH)-wildtype high-grade glioma. Methods We...

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Bibliographic Details
Main Authors: Nalee Kim, Se Hoon Kim, Seok-Gu Kang, Ju Hyung Moon, Jaeho Cho, Chang-Ok Suh, Hong In Yoon, Jong Hee Chang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Radiation Oncology
Subjects:
ATM
IDH-wild type high-grade glioma
Radiosensitivity
Next-generation sequencing
Radiation therapy
Online Access:http://link.springer.com/article/10.1186/s13014-020-01619-y

Internet

http://link.springer.com/article/10.1186/s13014-020-01619-y

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