Tumour-on-chip microfluidic platform for assessment of drug pharmacokinetics and treatment response
Petreus et al. describe a platform combining 3D tumour-on-chip technology and pump driven microfluidics to study drug effects at physiological exposures preclinically. They test colorectal cancer spheroids with combinations of two drugs and show that it can successfully predict efficacy in vivo, the...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02526-y |