Immune requirements of post-exposure immunization with modified vaccinia Ankara of lethally infected mice.

Current prophylactic vaccines work via the induction of B and T cell mediated memory that effectively control further replication of the pathogen after entry. In the case of therapeutic or post-exposure vaccinations the situation is far more complex, because the pathogen has time to establish itself...

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Bibliographic Details
Main Authors: Henning Lauterbach, Ronny Kassub, Juliane Pätzold, Jana Körner, Michael Brückel, Admar Verschoor, Paul Chaplin, Mark Suter, Hubertus Hochrein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2836377?pdf=render