Cholesterol Acceptors Regulate the Lipidome of Macrophage Foam Cells

Cholesterol Acceptors Regulate the Lipidome of Macrophage Foam Cells

Arterial foam cells are central players of atherogenesis. Cholesterol acceptors, apolipoprotein A-I (apoA-I) and high-density lipoprotein (HDL), take up cholesterol and phospholipids effluxed from foam cells into the circulation. Due to the high abundance of cholesterol in foam cells, most previous...

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Bibliographic Details
Main Authors: Antoni Paul, Todd A. Lydic, Ryan Hogan, Young-Hwa Goo
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
ABCA1
ABCG1
cholesterol
macrophage
foam cells
atherosclerosis
LDL
lipidome
lipidomics
mass-spectrometry
oxysterols
reverse cholesterol transport
Online Access:https://www.mdpi.com/1422-0067/20/15/3784

Internet

https://www.mdpi.com/1422-0067/20/15/3784

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