Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys

Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys

Abstract Background The initial envelope (Env)-specific antibody response in acutely HIV-1-infected individuals and simian immunodeficiency virus (SIV)-infected rhesus monkeys (RMs) is dominated by non-neutralizing antibodies targeting Env gp41. In contrast, natural primate SIV hosts, such as Africa...

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Bibliographic Details
Main Authors: Quang N. Nguyen, David R. Martinez, Jonathon E. Himes, R. Whitney Edwards, Qifeng Han, Amit Kumar, Riley Mangan, Nathan I. Nicely, Guanhua Xie, Nathan Vandergrift, Xiaoying Shen, Justin Pollara, Sallie R. Permar
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Retrovirology
Subjects:
SIV
Linear peptide antibody responses
Natural SIV host
African green monkey
Rhesus monkey
Antibody response
Online Access:http://link.springer.com/article/10.1186/s12977-018-0406-5

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http://link.springer.com/article/10.1186/s12977-018-0406-5

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