Investigating hypotheses of neurodegeneration by learning dynamical systems of protein propagation in the brain

Investigating hypotheses of neurodegeneration by learning dynamical systems of protein propagation in the brain

We introduce a theoretical framework for estimating, comparing and interpreting mechanistic hypotheses on long term protein propagation across brain networks in neurodegenerative disorders (ND). The model is expressed within a Bayesian non-parametric regression setting, where mechanisms of protein d...

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Bibliographic Details
Main Authors: Sara Garbarino, Marco Lorenzi
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:NeuroImage
Subjects:
Neurodegeneration
Causal model
Dynamical systems
Protein propagation
Gaussian process
Brain connectivity
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811921002573

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http://www.sciencedirect.com/science/article/pii/S1053811921002573

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