Reduced parasite motility and micronemal protein secretion by a p38 MAPK inhibitor leads to a severe impairment of cell invasion by the apicomplexan parasite Eimeria tenella.

Reduced parasite motility and micronemal protein secretion by a p38 MAPK inhibitor leads to a severe impairment of cell invasion by the apicomplexan parasite Eimeria tenella.

E. tenella infection is associated with a severe intestinal disease leading to high economic losses in poultry industry. Mitogen activated protein kinases (MAPKs) are implicated in early response to infection and are divided in three pathways: p38, extracellular signal-regulated protein kinase (ERK)...

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Bibliographic Details
Main Authors: Françoise I Bussière, Fabien Brossier, Yves Le Vern, Alisson Niepceron, Anne Silvestre, Thibaut de Sablet, Sonia Lacroix-Lamandé, Fabrice Laurent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4331428?pdf=render

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http://europepmc.org/articles/PMC4331428?pdf=render

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