Whole exome sequencing in thrombophilic pedigrees to identify genetic risk factors for venous thromboembolism.

Whole exome sequencing in thrombophilic pedigrees to identify genetic risk factors for venous thromboembolism.

BACKGROUND:Family studies have shown a strong heritability component for venous thromboembolism (VTE), but established genetic risk factors are present in only half of VTE patients. AIM:To identify genetic risk factors in two large families with unexplained hereditary VTE. METHODS:We performed whole...

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Bibliographic Details
Main Authors: Marisa L R Cunha, Joost C M Meijers, Frits R Rosendaal, Astrid van Hylckama Vlieg, Pieter H Reitsma, Saskia Middeldorp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5695603?pdf=render

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http://europepmc.org/articles/PMC5695603?pdf=render

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