Sodium butyrate prevents radiation-induced cognitive impairment by restoring pCREB/BDNF expression

Sodium butyrate prevents radiation-induced cognitive impairment by restoring pCREB/BDNF expression

Sodium butyrate is a histone deacetylase inhibitor that affects various types of brain damages. To investigate the effects of sodium butyrate on hippocampal dysfunction that occurs after whole-brain irradiation in animal models and the effect of sodium butyrate on radiation exposure-induced cognitiv...

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Bibliographic Details
Main Authors: Hae June Lee, Yeonghoon Son, Minyoung Lee, Changjong Moon, Sung Ho Kim, In Sik Shin, Miyoung Yang, Sangwoo Bae, Joong Sun Kim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
sodium butyrate; radioprotector; ionizing radiation; hippocampal damage; cAMP response element binding; brain-derived neurotrophic factor; histone deacetylase inhibitor; neurogenesis
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=9;spage=1530;epage=1535;aulast=Lee

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=9;spage=1530;epage=1535;aulast=Lee

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