Aberrant Function and Long-Term Survival of Mouse β Cells Exposed In Vitro to High Glucose Concentrations
In vitro culture of murine Langerhans islets usually ends in islet death after 1-3 wk. Given contradictory published data, we studied the influence of glucose on the function and survival of islets from DBA/2 mice. Islets were cultured on plastic microwells, using 1, 2, or 11 g/l glucose concentrati...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
1994-09-01
|
| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/096368979400300512 |