A Defined Combination of Four Active Principles From the Danhong Injection Is Necessary and Sufficient to Accelerate EPC-Mediated Vascular Repair and Local Angiogenesis

A Defined Combination of Four Active Principles From the Danhong Injection Is Necessary and Sufficient to Accelerate EPC-Mediated Vascular Repair and Local Angiogenesis

Many compounds in Chinese medicine formulae, including Danhong injection (DHI) formulae, are capable of stimulating angiogenesis and promoting vascular repair, but their chemical basis and action mechanisms remain poorly defined. The aim of this study is to determine the minimal native chemical comp...

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Bibliographic Details
Main Authors: Shuang He, Hao Guo, Tiechan Zhao, Yanzhi Meng, Rongrong Chen, Jie Ren, Lanlan Pan, Guanwei Fan, Miaomiao Jiang, Gangjian Qin, Yan Zhu, Xiumei Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
ischemic vascular injury disease
Danhong injection
angiogenesis
EPCs
activity reconstitution
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01080/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01080/full

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