Mobility of Nucleostemin in Live Cells Is Specifically Related to Transcription Inhibition by Actinomycin D and GTP-Binding Motif

In vertebrates, nucleostemin (NS) is an important marker of proliferation in several types of stem and cancer cells, and it can also interact with the tumor-suppressing transcription factor p53. In the present study, the intra-nuclear diffusional dynamics of native NS tagged with GFP and two GFP-tag...

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Bibliographic Details
Main Authors: Chan-Gi Pack, Keehoon Jung, Bjorn Paulson, Jun Ki Kim
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
DRB
Online Access:https://www.mdpi.com/1422-0067/22/15/8293