Specific extracellular matrix remodeling signature of colon hepatic metastases.

To identify genes implicated in metastatic colonization of the liver in colorectal cancer, we collected pairs of primary tumors and hepatic metastases before chemotherapy in 13 patients. We compared mRNA expression in the pairs of patients to identify genes deregulated during metastatic evolution. W...

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Bibliographic Details
Main Authors: Maguy Del Rio, Caroline Mollevi, Nadia Vezzio-Vie, Frédéric Bibeau, Marc Ychou, Pierre Martineau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3762755?pdf=render