17β-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss

17β-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss

In addition to regulating reproductive functions in the brain and periphery, estrogen has tropic and neuroprotective functions in the central nervous system (CNS). Estrogen administration has been demonstrated to provide protection in several animal models of CNS disorders, including stroke, brain i...

Full description

Bibliographic Details
Main Authors: Lorelei C. Taylor, Kasturi Puranam, Wendy Gilmore, Jenny P-Y. Ting, Glenn K. Matsushima
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Neurobiology of Disease
Subjects:
Demyelination
Myelin
Cuprizone
Estrogen
E2
17β-estradiol
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110000884

Internet

http://www.sciencedirect.com/science/article/pii/S0969996110000884

Similar Items