Changes of Coenzyme A and Acetyl-Coenzyme A Concentrations in Rats after a Single-Dose Intraperitoneal Injection of Hepatotoxic Thioacetamide Are Not Consistent with Rapid Recovery

Changes of Coenzyme A and Acetyl-Coenzyme A Concentrations in Rats after a Single-Dose Intraperitoneal Injection of Hepatotoxic Thioacetamide Are Not Consistent with Rapid Recovery

Small biomolecules, such as coenzyme A (CoA) and acetyl coenzyme A (acetyl-CoA), play vital roles in the regulation of cellular energy metabolism. In this paper, we evaluated the delayed effect of the potent hepatotoxin thioacetamide (TAA) on the concentrations of CoA and acetyl-CoA in plasma and in...

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Bibliographic Details
Main Authors: Yevgeniya I. Shurubor, Arthur J. L. Cooper, Andrey B. Krasnikov, Elena P. Isakova, Yulia I. Deryabina, M. Flint Beal, Boris F. Krasnikov
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
acetyl-coenzyme A
coenzyme A
hepatic encephalopathy
high performance liquid chromatography
thioacetamide
Online Access:https://www.mdpi.com/1422-0067/21/23/8918

Internet

https://www.mdpi.com/1422-0067/21/23/8918

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