Progesterone to prevent miscarriage in women with early pregnancy bleeding: the PRISM RCT

Progesterone to prevent miscarriage in women with early pregnancy bleeding: the PRISM RCT

Background: Progesterone is essential for a healthy pregnancy. Several small trials have suggested that progesterone therapy may rescue a pregnancy in women with early pregnancy bleeding, which is a symptom that is strongly associated with miscarriage. Objectives: (1) To assess the effects of vagina...

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Main Authors: Arri Coomarasamy, Hoda M Harb, Adam J Devall, Versha Cheed, Tracy E Roberts, Ilias Goranitis, Chidubem B Ogwulu, Helen M Williams, Ioannis D Gallos, Abey Eapen, Jane P Daniels, Amna Ahmed, Ruth Bender-Atik, Kalsang Bhatia, Cecilia Bottomley, Jane Brewin, Meenakshi Choudhary, Fiona Crosfill, Shilpa Deb, W Colin Duncan, Andrew Ewer, Kim Hinshaw, Thomas Holland, Feras Izzat, Jemma Johns, Mary-Ann Lumsden, Padma Manda, Jane E Norman, Natalie Nunes, Caroline E Overton, Kathiuska Kriedt, Siobhan Quenby, Sandhya Rao, Jackie Ross, Anupama Shahid, Martyn Underwood, Nirmala Vaithilingham, Linda Watkins, Catherine Wykes, Andrew W Horne, Davor Jurkovic, Lee J Middleton
Format: Article
Language:English
Published: NIHR Journals Library 2020-06-01
Series:Health Technology Assessment
Subjects:
threatened miscarriage
progesterone
live birth
early pregnancy vaginal bleeding
first trimester
randomised controlled trial
Online Access:https://doi.org/10.3310/hta24330

Internet

https://doi.org/10.3310/hta24330

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