Comparative Analysis of Matrix Metalloproteinase Family Members Reveals That MMP9 Predicts Survival and Response to Temozolomide in Patients with Primary Glioblastoma.

Comparative Analysis of Matrix Metalloproteinase Family Members Reveals That MMP9 Predicts Survival and Response to Temozolomide in Patients with Primary Glioblastoma.

BACKGROUND:Glioblastoma multiform (GBM) is the most common malignant primary brain tumor in adults. Radiotherapy plus concomitant and adjuvant TMZ chemotherapy is the current standard of care for patients with GBM. Matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, are key...

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Bibliographic Details
Main Authors: Qingbin Li, Baoshi Chen, Jinquan Cai, Ying Sun, Guangzhi Wang, Yongli Li, Ruiyan Li, Yan Feng, Bo Han, Jianlong Li, Yu Tian, Liye Yi, Chuanlu Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4811585?pdf=render

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http://europepmc.org/articles/PMC4811585?pdf=render

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