Lateral Lymph Node Metastases in Locally Advanced Low Rectal Cancers May Not Be Treated Effectively With Neoadjuvant (Chemo)Radiotherapy Only

Lateral Lymph Node Metastases in Locally Advanced Low Rectal Cancers May Not Be Treated Effectively With Neoadjuvant (Chemo)Radiotherapy Only

Background: In the West, pre-treatment abnormal lateral lymph nodes (LLN+) in patients with a low locally advanced rectal cancer (AJCC Stage III), are treated with neoadjuvant (chemo)radiotherapy (nCRT), without a lateral lymph node dissection (LLND). It has been suggested, however, that LLN+ patien...

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Bibliographic Details
Main Authors: Anouck Haanappel, Hidde M. Kroon, Dennis P. Schaap, Sergei Bedrikovetski, Nagendra N. Dudi-Venkata, Hong X. Lee, Michelle L. Thomas, Jianliang Liu, Maxime J. M. van der Valk, Harm J. T. Rutten, Geerard L. Beets, Miranda Kusters, Tarik Sammour
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
lateral lymph nodes
locally advanced low rectal cancer
neoadjuvant (chemo)radiotherapy
oncological outcomes
survival
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01355/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01355/full

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