Vav1 Down-Modulates Akt2 Expression in Cells from Pancreatic Ductal Adenocarcinoma: Nuclear Vav1 as a Potential Regulator of Akt Related Malignancy in Pancreatic Cancer

Vav1 Down-Modulates Akt2 Expression in Cells from Pancreatic Ductal Adenocarcinoma: Nuclear Vav1 as a Potential Regulator of Akt Related Malignancy in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive tumor malignancy worldwide, mainly due to uncontrolled metastasis. Among the numerous molecules deregulated in PDAC, different members of the Akt pathways are of great importance because they are involved in tumor cell proliferation, mig...

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Bibliographic Details
Main Authors: Silvia Grassilli, Federica Brugnoli, Rossano Lattanzio, Simonetta Buglioni, Valeria Bertagnolo
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
pancreatic ductal adenocarcinoma
Vav1
targeting Akt pathways
Online Access:https://www.mdpi.com/2227-9059/8/10/379

Internet

https://www.mdpi.com/2227-9059/8/10/379

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