Inducing secondary metabolite production of Aspergillus sydowii through microbial co-culture with Bacillus subtilis

Abstract Background The co-culture strategy which mimics natural ecology by constructing an artificial microbial community is a useful tool to activate the biosynthetic gene clusters to generate new metabolites. However, the conventional method to study the co-culture is to isolate and purify compou...

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Bibliographic Details
Main Authors: Yu Sun, Wen-Cai Liu, Xuan Shi, Hai-Zhou Zheng, Zhi-Hui Zheng, Xin-Hua Lu, Yan Xing, Kai Ji, Mei Liu, Yue-Sheng Dong
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-021-01527-0