Rosuvastatin attenuates piroxicam-mediated gastric ulceration and hepato-renal toxicity in rats

Rosuvastatin attenuates piroxicam-mediated gastric ulceration and hepato-renal toxicity in rats

Piroxicam (Px) is a non-steroidal anti-inflammatory drug that is widely prescribed in various inflammatory disorders. However, Px is known to induce gastric ulceration and hepato-renal toxicity. Rosuvastatin (ROSV), a member of the statin family, has anti-inflammatory and antioxidant actions indepen...

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Bibliographic Details
Main Authors: Ahmed Abdeen, Mohamed Aboubakr, Dina Elgazzar, Mohamed Abdo, Afaf Abdelkader, Samar Ibrahim, Ashraf Elkomy
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Piroxicam
Rosuvastatin
Gastric ulcer
Hepato-renal toxicity
Lipid peroxidation
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221837080X

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http://www.sciencedirect.com/science/article/pii/S075333221837080X

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