Dickkopf-related protein 3 alters aerobic glycolysis in pancreatic cancer BxPC-3 cells, promoting CD4+ T-cell activation and function

Dickkopf-related protein 3 alters aerobic glycolysis in pancreatic cancer BxPC-3 cells, promoting CD4+ T-cell activation and function

Abstract Background To investigate the value of Dickkopf-related protein 3 (DKK3) on aerobic glycolysis in pancreatic cancer cells, where DKK3-overexpression is used to determine its effects on CD4+ T cells. Methods The BxPC-3-DKK3 cell line was constructed, and peripheral blood mononuclear cell (PB...

Full description

Bibliographic Details
Main Authors: Qingqu Guo, Yiming Chu, Hongbo Li, Dike Shi, Lele Lin, Weifeng Lan, Dan Wu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:European Journal of Medical Research
Subjects:
Dickkopf-related protein 3
Pancreatic cancer
β-catenin
CD4+ T cells
Aerobic glycolysis
Online Access:https://doi.org/10.1186/s40001-021-00567-x

Internet

https://doi.org/10.1186/s40001-021-00567-x

Similar Items