Trehalose Reduces Nerve Injury Induced Nociception in Mice but Negatively Affects Alertness

Trehalose Reduces Nerve Injury Induced Nociception in Mice but Negatively Affects Alertness

Trehalose, a sugar from fungi, mimics starvation due to a block of glucose transport and induces Transcription Factor EB- mediated autophagy, likely supported by the upregulation of progranulin. The pro-autophagy effects help to remove pathological proteins and thereby prevent neurodegenerative dise...

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Bibliographic Details
Main Authors: Vanessa Kraft, Katja Schmitz, Annett Wilken-Schmitz, Gerd Geisslinger, Marco Sisignano, Irmgard Tegeder
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Nutrients
Subjects:
spared nerve injury
nociception
IntelliCage
learning and memory
fungal sugar
Online Access:https://www.mdpi.com/2072-6643/13/9/2953

Internet

https://www.mdpi.com/2072-6643/13/9/2953

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