Inactivation of by promoter methylation correlated with lymph node metastasis and genomic instability in nasopharyngeal carcinoma

This study aimed to investigate the inactivation of the parkin gene by promoter methylation and its relationship with genome instability in nasopharyngeal carcinoma. Parkin was considered as a tumor suppressor gene in various types of cancers. However, its role in nasopharyngeal carcinoma is unexplo...

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Bibliographic Details
Main Authors: Haifeng Ni, Zhen Zhou, Bo Jiang, Xiaoyang Yuan, Xiaolin Cao, Guangwu Huang, Yong Li
Format: Article
Language:English
Published: IOS Press 2017-03-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317695025