Ascorbic Acid Mitigates D-galactose-Induced Brain Aging by Increasing Hippocampal Neurogenesis and Improving Memory Function

Ascorbic acid is essential for normal brain development and homeostasis. However, the effect of ascorbic acid on adult brain aging has not been determined. Long-term treatment with high levels of D-galactose (D-gal) induces brain aging by accumulated oxidative stress. In the present study, mice were...

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Main Authors: Sung Min Nam, Misun Seo, Jin-Seok Seo, Hyewhon Rhim, Sang-Soep Nahm, Ik-Hyun Cho, Byung-Joon Chang, Hyeon-Joong Kim, Sun-Hye Choi, Seung-Yeol Nah
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/11/1/176